张巨峰，教授，博士，生物工程系主任

科研项目：广东省科技计划；国家自然科学基金面上项目；中国博士后科学基金；深港创新圈计划；广东省自然科学基金。

主要研究论文：

1.Zhang J, Wang D, Xiong J, Chen L, Huang J. MicroRNA-33a-5p suppresses growth of osteosarcoma cells and is downregulated in human osteosarcoma. Oncol Lett. 2015;10(4):2135-2141.

2.Zhang J, Luo X, Li H, Yue X, Deng L, Cui Y, Lu Y. MicroRNA-223 functions as an oncogene in human colorectal cancer cells. Oncol Rep. 2014 ;32(1):115-20

3.Zhang J, Luo X, Li H, Deng L, Wang Y. Genome-wide uncovering of STAT3-mediated miRNA expression profiles in colorectal cancer cell lines. Biomed Res Int. 2014:187105

4.Zhang J, Lu Y, Yue X, Li H, Luo X, Wang Y, Wang K, Wan J, MiR-124 Suppresses Growth of Human Colorectal Cancer by Inhibiting STAT3. PLoS One, 2013; 8 (8), e70300.

5.Zhang J, Wang Y, Zhen P, Luo X, Zhang C, Zhou L, Lu Y, Yang Y, Zhang W, Wan J. Genome-wide analysis of miRNA signature differentially expressed in doxorubicin-resistant and parental human hepatocellular carcinoma cell lines. PLoS One. 2013;8(1):e54111. doi: 10.1371/journal.pone.0054111.

6.Zhang J, Wei F, Wang H, Li H, Qiu W, Ren P, Chen X, Huang Q. A novel oncolytic adenovirus expressing Escherichia coli cytosine deaminase exhibits potent antitumor effect on human solid tumors. Cancer Biother Radiopharm. 2010 ;25(4):487-95.

7.Zhang J, Deng J, Zhang C, Lu Y, Liu L, Wu Q, Shao Y, Zhang J, Yang H, Yu B, Wan J.Association of GSTT1, GSTM1 and CYP1A1 polymorphisms with susceptibility to systemic lupus erythematosus in the Chinese population. Clin Chim Acta. 2010 ;411(11-12):878-81.

8.Zhang J, Wei F, Wang HP, Li HM, Qiu W, Ren PK, Chen XF, Huang Q. Potent anti-tumor activity of telomerase-dependent and HSV-TK armed oncolytic adenovirus for non-small cell lung   cancer in vitro and in vivo. J Exp Clin Cancer Res. 2010 ;29:52-56.

9.Zhang J, Wang Z, Wei F, Qiu W, Zhang L, Huang Q. Computational modeling and functional analysis of Herpes simplex virus type-1 thymidine kinase and Escherichia coli cytosine deaminase fusion protein. Biochem Biophys Res Commun. 2007;360(1):46-50.